The Pirates handed the Bulls just their fourth loss in league play in a 3-2 decision at the ECU Softball Stadium.
With the win the Pirates improve to 28-9 overall and 6-4 in league play.
No. 8 North Carolina got out to a big lead with five runs in the second inning and never looked back as the Tar Heels captured a series-opening 9-3 win over Georgia Tech on Friday night at Boshamer Stadium.
ECU had AAC leader USF down to its last strike, but the Bulls managed to rally for five runs with two outs in the top of the seventh inning to walk away with a 7-3 victory over the Pirates.