#24 ECU faced #14 Rice Saturday for the second game in their series in Texas.
ECU took a 1-0 lead in the top of the first with Drew Reynolds scoring off a double by John Wooten.
J.T. Chargois tied the game for the Rice Owls in the bottom of the third.
The score would stay tied at 1 until the top of the eighth.
Philip Clark's RBI single to center put the Pirates up 2-1 but Rice had an answer in the bottom of the eighth when Shane Hoelscher hit a solo home run to center field.
The game remained tied again all the way into extra innings.
That was until Craig Manuel hit a walk-off grand slam in the tenth to lift the Rice Owls to a 6-2 victory.
ECU and Rice will conclude the series Sunday afternoon at Noon.