Two popular anti-smoking drugs will now carry a boxed warning.
FDA officials say a new warning will be added to Chantix and Zyban, highlighting the increased risk for changes in behavior, depressed mood, hostility and suicidal thoughts.
Since these drugs have been on the market, the FDA has received reports of 98 suicides and 188 attempts linked to Chantix. There have been 14 suicides and 17 attempts linked to Zyban.
Experts say it is hard to differentiate between normal nicotine withdrawal symptoms, and those caused by these drugs, but they say a majority of patients noticed these symptoms once they started treatment, and they went away after they stopped the drug.
However, some patients did experience side effects after they stopped treatment, leading experts to recommend continued screening while a patient is on and off the drugs.