Yahya Jammeh, who seized power in a coup in 1994, once vowed to rule for a billion years.
Not a single arrest was made as hundreds of thousands marched in the nation's capital, some in opposition to President Donald Trump.
Organizers expect more than 200,000 demonstrators to gather in Washington, D.C., Saturday to march in support of gender and other issues.
From Washington, D.C., to Chicago, Denver and Los Angeles, hundreds of thousands of women turned out to demonstrate for their rights.
Trump's visit was seen as a way to mend fences, but was criticized for a speech seen as lacking respect for the CIA's Memorial Wall of Agency heroes.