Officials say House Majority Leader Eric Cantor intends to resign his leadership post this summer after losing a primary election Tuesday night in a major upset.
The officials say Cantor is expected to make a formal announcement of his plans later in the day at a closed-door meeting of the party's rank and file.
The decision would clear the way for a leadership shake-up just months before midterm elections with control of the House at stake.
Cantor's office declined to comment. The officials who described his plans did so on condition of anonymity, saying they were not authorized to pre-empt an official announcement.
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House Majority Leader Eric Cantor has been defeated by a tea party-backed challenger in the Republican primary.
Economics professor Dave Brat won a stunning upset victory against Cantor on Tuesday in the 7th District Republican primary contest, which is in the Richmond area.
Cantor is the second-most powerful member of the U.S. House and was seen by some as a possible successor to the House speaker.
His loss to a political novice with little money marks a huge victory for the tea party movement, which supported Cantor just a few years ago.
Brat had been a thorn in Cantor's side on the campaign, casting the congressman as a Washington insider who isn't conservative enough. Last month, a feisty crowd of Brat supporters booed Cantor in front of his family at a local party convention.